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Just Got A Spironolactone Script, Question About Hormones

Discussion in 'Women's General Hair Loss Discussions' started by losing_it, Jan 19, 2018.

  1. losing_it

    losing_it Established Member

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    Hey ladies! I went to a new doctor yesterday and she gave me a script for 2% Nizoral (I currently use 1%) and Spironolactone 50mg to start and movingly to 100mg in a few weeks.

    She looked at my scalp with the microscope thing and said she saw a few miniaturized hairs but said I was “very early in the game.” I was kind of sad to see the miniaturization but I also wasn’t shocked.

    Anyway my question is... last time I got my hormones checked my testosterone was actually a little low. DHEAs and estrogen/progesterone were normal. But given the low testosterone would Spironolactone even theoretically work for me?

    I’m willing to give it a shot, but of course I’m nervous because it’s always nerve racking to start a new med! What do you guys think?
     
  2. valentinab00

    valentinab00 Established Member

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    That’s a good question. I had low T as well and have been taking Spironolactone for a few months. It lowered my T and DHT, but I have seen no improvement in hair growth. I sometimes wonder if low T is the problem, but am then concerned about taking any T because of DHT.
     
  3. losing_it

    losing_it Established Member

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    Sorry to hear you haven't seen any regrowth! Have you seen a reduction in shedding at all? And what dose are you taking?

    The doctor also wanted me to get my Vit D and Zinc levels drawn prior to starting Spironolactone just to make sure there aren't any major deficiencies. I remember reading somewhere that you thought Zinc was the cause of your hair loss. Any thoughts on that now?
     
  4. valentinab00

    valentinab00 Established Member

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    Your doctor should check your potassium levels really while on Spironolactone. Doesn’t hurt to check the others for your health. I take 100 orally and also use a topical from time to time, same dose. My decrease in shedding is due to either less hair to lose so the percentage loss is the same or taking rogaine. The zinc was another member. My hair loss is hormonal.
     
  5. losing_it

    losing_it Established Member

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    Oh yes, you're right! I think it was Barbina!

    I meant that she told me to check Vitamin D and Zinc prior to starting Spironolactone because I have never had them checked and they could be a cause of hair loss that could be corrected through supplements. Not that the Spironolactone would cause issues with them. Sorry, that was probably confusing.
     
  6. valentinab00

    valentinab00 Established Member

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    Yep, Barbina.

    Best wishes. Keep us posted.
     
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  7. hoping4best

    hoping4best Established Member

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    I also have low T (am post menopausal as of my late 30s). I was advised not to take finasteride or spirnolactone as a result, so I am trying compounded topical finasteride + minoxidil. 18 months or so on minoxidil alone did help me regrow some hair, but my shedding never lets up, ever. So I’m experimenting. I know that female pattern hair loss is not always androgen or DHT related. I suspect mine is not due to DHT, but I’m trying to see if I can find out.
     
  8. valentinab00

    valentinab00 Established Member

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    Serum DHT levels versus enzymatic conversion at the scalp level I wish I knew. The hair loss mechanism would seem to be DHT. It would be interesting to know what is causing the loss.
     
  9. losing_it

    losing_it Established Member

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    Interesting... who advised you of that? I mentioned it to my doctor and she didn’t really say anything, but we talked about a lot of things before she prescribed Spironolactone, so I’m not sure if she forgot about it by the time she decided to prescribe it.
     
  10. losing_it

    losing_it Established Member

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    I have read that low testosterone can cause hair loss too, though. It's just so much information to absorb. Hormones are crazy complicated.
     
    #10 losing_it, Jan 21, 2018
    Last edited: Jan 21, 2018
  11. valentinab00

    valentinab00 Established Member

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    I’ve read that too.
     
  12. hoping4best

    hoping4best Established Member

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    My reproductive endocrinologist (menopause specialist) didn’t want me on systemic androgen reducers because of my low androgens, but he’s ok with me trying them topically.
     
  13. losing_it

    losing_it Established Member

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    Interesting! Just curious... have you had your zinc levels drawn? I've been reading that zinc is important for proper testosterone production. And that it is important for healthy hair growth. I'm getting mine drawn today. I don't think it'll be a miracle answer, but it might be a piece of the puzzle.
     
  14. hoping4best

    hoping4best Established Member

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    My zinc was low but I’ve been supplementing for a long time now, and it’s normal at this point. Good luck!
     
  15. hair of the dog

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    Losing_it did you get your zinc results? Was it low ?
     
  16. losing_it

    losing_it Established Member

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    My Vitamin D was 34, and my Zinc was 71. The hair specialist said she likes to see 30 at the very minimum for vitamin D and between 60 and 130 (ideally on the higher end of that range) for zinc. So I am currently supplementing both, but not going crazy. I take the supplement about every other day or 3 times per week. Sometimes I worry that over supplementing can cause issues too, so I'm trying to avoid that. I'll probably have my labs redrawn in a couple months to see if the supplementing helped!

    I'm waiting a couple months before I try Spironolactone. It seems my shedding has been decreasing, so I want to see if it is a real trend, or if it's just a fluke. If it's a fluke, I'll probably try the Spironolactone as kind of a last ditch effort.
     
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  17. Hairmess

    Hairmess Member

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    Hey losing it,

    If you decide to start Spironolactone keep us updated. Two months ago I got hormone labs drawn which revealed elevated testosterone (54) and low progesterone (0.4 during luteal phase)
    I'm concerned that the elevated testosterone is contributing to my hair loss/aggressive shedding. Especially considering my progesterone is quite low, putting everything out of balance. I have slight hirsutism ( I pluck the little dark hairs that pop up every two days on my chin and below my belly button so I should have known testosterone might be an issue for me) Not sure if this is PCOS. I'm active and fairly thin and my periods are heavy but regular. I did have ovarian cysts 10 years ago after I didn't have a period for almost a year. At the time I attributed that to an eating disorder but who knows!

    I have started bio identical progesterone cream about 2-3 weeks ago and added vitex, nettle root and licorice/peony to naturally restore progesterone and lower testosterone. Supplements suggested by NP Lara Briden. Her site is pretty interesting regarding female hormones, BCP and PCOS.
    I am apprehensive to try synthetic hormones or an anti-androgen to lower testosterone but at the same time I'm losing faith in natural methods..but I will give the cream and supplements another 3 months. I want my body to just produce the right amount of hormones naturally!

    It's been 4.5 months post discontinuation of rogaine and my shed is high, just as high as it was while on it. I wake up everyday with a hair covered shirt and pillow. It's so very frustrating. Do I give my self more time to recover this shedding phase or do I move on to yet another treatment that may exacerbate and prolong this heavy shed? Before rogaine my shed was never like this.. I'm always teetering on the hope that maybe I haven't tried the right treatment and the fear of making things worse. Arghh!!

    Well off to get an endo referall. The one doctor I have not seen yet.
    I hope everyone is well
     
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  18. losing_it

    losing_it Established Member

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    Hey there! I am still trying to decide whether or not to try Spironolactone. I told myself to give it until April since my shedding has been down for the last two months. If you read any of my history here, you will see that I had respite from hair loss a few years ago where my shedding stopped and my hair grew completely back in. When that happened, I noticed my hair was feeling healthier and fuller BEFORE I really noticed a decrease in shedding. This time, my shedding has slowed (not completely gone, but wayyy better), but I don't feel that healthier/fuller hair, so I'm not convinced that it's really turning around like it did last time. I thought I would have more answers by April, but it's rapidly approaching, and I'm still conflicted!

    I also have mild hirsutism (I wax my lip weekly and I have some a couple hairs that I pluck around my nipple), but I've always been a hairier girl... I always attributed it to my French/Greek background, but who knows.

    My testosterone is a lot lower than yours (22 serum and 0.6 direct) and my progesterone is a lot higher (22 during luteal phase). Estrogen was 76. My DHEAs was around 250 too, so not elevated at all. That's one of my biggest concerns with Spironolactone... I don't want to lower my testosterone and have side effects from that. But then of course they say that your testosterone could be normal, but your body is just particularly sensitive to it. I wish there was a more definitive test, but I guess we have to work with what we got.

    I also need to see an Endo! Unfortunately I have shit for insurance, so I order my own labs and pay out of pocket and then analyze them on my own. I should have better insurance in a year or so, but my hair might be really bad by then. Frustrating for sure!
     
  19. Jtilly

    Jtilly Established Member

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    Hi everyone! I am new to this site and new to hair loss.
    So my story goes, and I’ll try to make this short, in December I had super thick hair. Even had stylist thin it out.
    By February I felt it was a bit wispy at the bottom. Stylist said no, it’s just how we cut it. By end of April I was more concerned, went to OB in early May, was diagnosed with early menopause or peri menopause, depending on which one of my hundred doctors I’ve seen you ask.
    So they give me estradiol pill. Took for 5 days, had bad reactions. They put me on estradiol patch for 5 weeks, bad reactions still really bad, they add Prometrium, helped for a week and a half. By early July I’m having acne that I developed the second I started estradiol in May, I did not have acne beforehand, I’m having massive anxiety I didn’t have before, increased night sweats, only had a few before HRT, having facial swelling, too many other reactions to list, AND my hair started shedding early July! So they take me off HRT in early July. I see 2 hormone “specialists” who tell me I’m peri menopause and need progesterone only. So... I take 100mg progesterone for 7 days. More bad reactions!
    Then I see an OB at world renowned
    Mayo Clinic who tells me I need to go on Alesse birth control. Say what now?? So I look into it because now I don’t trust any doctors. And guess what? Alesse birth control has high androgen activity!! Um... Apparently she didn’t hear me say I’m concerned about the hair I’m losing and I’m having acne I didn’t have before. Further more she was mad at me for questioning her advice!
    Throughout all of this I saw 3 dermatologists, including one at Mayo Clinic. They all keep telling me my hair is fine and I’m just experiencing telogen effluvium. Gah!
    I saw a 4th dermatologist who said I have telogen effluvium and androgenetic alopecia. She herself suffers from both. She did a biopsy which confirmed her opinion.
    She is recommendeding Yaz, 50mg spironolactone, and rogaine. She uses rogaine herself everyday, has used BCP and spironolactone in the past and has beautiful head of hair.
    So here I am... Went from mildly concerned about my hair in May, 4 months later losing hair by the buckets every day now! I’ve lost 50 percent of my hair.
    I am terrified of all these meds! All I see is how people lose more hair on BCP, spironolactone and Rogaine.
    I know my estrogen and progesterone are very low or wildly fluctuating. My testosterone and DHT are “normal”, actually on the low end. But perhaps I am sensitive to the testosterone and DHT due to even lower female hormones???
    So I’m confused if spironolactone will make matters worse?
    I am continuing to battle acne and hair loss and I’m so lost, confused and terrified.
    Have any of you used spironolactone, BCP or rogaine? Have you had any successes??
    Hope someone sees this!
    Thank you!!
     
  20. Jtilly

    Jtilly Established Member

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    Also have any of you been diagnosed with androgenetic alopecia?
    Thank you again!
     

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