I've been using Retin-A 0.1% on my face off & on for several years. I never connected it with hair loss. I noticed mine shedding last August, but I have no way of knowing if it's the RA or not. How could I possibly pinpoint that? I have a history of female hair loss in my family, so I tend to blame that rather than Retin-A. Plus I don't get any of the gel in or near my hair.